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1142 lines
36 KiB
HTML
1142 lines
36 KiB
HTML
<!DOCTYPE html>
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<html lang='en'>
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<head>
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<meta charset='utf-8' />
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<meta name='viewport' content='width=device-width, initial-scale=1' />
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<title>Turn a Study into a Lab Meeting Deck like a Senior Postdoc - Academic research</title>
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<meta name='description' content='A gut-microbiome lab-meeting research deck on kami parchment. Warm parchment with ink-blue cover and chapter slides, serif at one weight, no italic.' />
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<link rel='preconnect' href='https://fonts.googleapis.com' />
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<link rel='preconnect' href='https://fonts.gstatic.com' crossorigin />
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<link href='https://fonts.googleapis.com/css2?family=Source+Serif+4:wght@400;500&family=Source+Sans+3:wght@400;500&family=JetBrains+Mono:wght@400;500&display=swap' rel='stylesheet' />
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<style>
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/*
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* kami-deck — single-file slide deck stylesheet.
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*
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* Kami token language (warm parchment, ink-blue accent, serif at one
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* weight, no italic) — but laid out as a horizontal swipe deck. Macro
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* tokens are scaled × ~1.6 vs. print baseline; letter-spacing scaled
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* × ~0.6 (per design-systems/kami/DESIGN.md §3).
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*
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* Navigation model is borrowed from skills/guizang-ppt — same flex
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* track + transform translateX, same key/wheel/touch handlers.
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*/
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:root {
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/* surface */
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--parchment: #f5f4ed;
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--ivory: #faf9f5;
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/* brand (single chromatic accent) */
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--brand: #1B365D;
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--brand-light: #2D5A8A;
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--brand-steel: #B5C8DC; /* highlight ink on navy: cover/end .hl */
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/* text */
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--near-black: #141413;
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--dark-warm: #3d3d3a;
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--olive: #504e49;
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--stone: #6b6a64;
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/* border */
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--border: #e8e6dc;
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--border-soft: #e5e3d8;
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/* tag tints (solid hex, NEVER rgba) */
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--tag-08: #EEF2F7;
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||
--tag-14: #E4ECF5;
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/* type */
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--serif: 'Source Serif 4', Charter, Georgia, Palatino, 'Times New Roman', serif;
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--sans: 'Source Sans 3', -apple-system, BlinkMacSystemFont, 'Segoe UI', system-ui, sans-serif;
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--mono: 'JetBrains Mono', 'SF Mono', 'Fira Code', Consolas, Monaco, monospace;
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}
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* { box-sizing: border-box; margin: 0; padding: 0; }
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html, body {
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width: 100%; height: 100%;
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overflow: hidden;
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||
background: var(--parchment);
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color: var(--near-black);
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font-family: var(--serif);
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font-weight: 400;
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-webkit-font-smoothing: antialiased;
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}
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strong { font-weight: 500; }
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/* ---------- deck flex track ---------- */
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#deck {
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position: fixed; inset: 0;
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height: 100vh;
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display: flex;
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flex-wrap: nowrap;
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transition: transform 0.9s cubic-bezier(0.77, 0, 0.175, 1);
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z-index: 5;
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will-change: transform;
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}
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.slide {
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width: 100vw; height: 100vh;
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flex: 0 0 100vw;
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position: relative;
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padding: 80px 96px;
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display: flex;
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flex-direction: column;
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overflow: hidden;
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background: var(--parchment);
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color: var(--near-black);
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}
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.slide.dark {
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background: var(--brand);
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color: var(--ivory);
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||
}
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.slide-inner {
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||
max-width: 1280px;
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||
margin: 0 auto;
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||
width: 100%;
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||
height: 100%;
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||
display: grid;
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||
align-content: center;
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||
gap: 24px;
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position: relative;
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||
min-height: 0;
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}
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||
/* ---------- per-slide chrome strip ---------- */
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.slide-chrome {
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position: absolute;
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top: 28px; left: 0; right: 0;
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display: flex;
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||
justify-content: space-between;
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||
align-items: center;
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||
padding: 0 96px;
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||
font-family: var(--sans);
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font-size: 11px;
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font-weight: 500;
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letter-spacing: 0.6px;
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text-transform: uppercase;
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color: var(--stone);
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z-index: 4;
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||
pointer-events: none;
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||
}
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||
.slide.dark .slide-chrome { color: rgba(250, 249, 245, 0.74); } /* 11px caps on navy: keep >= AA */
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.slide-chrome b { color: var(--near-black); font-weight: 500; }
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.slide.dark .slide-chrome b { color: var(--ivory); }
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.slide-chrome .left { display: inline-flex; align-items: center; gap: 12px; }
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||
.slide-chrome .right {
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||
display: inline-flex; align-items: center; gap: 12px;
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||
font-variant-numeric: tabular-nums;
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||
}
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||
.slide-chrome .mark {
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||
/* printer's mark: square hairline seal, not a generic pill chip */
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||
height: 22px;
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padding: 0 9px;
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border-radius: 2px;
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border: 1px solid currentColor;
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display: inline-flex;
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||
align-items: center;
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||
justify-content: center;
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||
font-family: var(--serif);
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||
font-weight: 500;
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||
font-size: 11px;
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||
letter-spacing: 0.5px;
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||
text-transform: lowercase;
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||
opacity: 0.85;
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||
}
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.slide-foot {
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||
position: absolute;
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||
bottom: 28px; left: 0; right: 0;
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||
display: flex;
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justify-content: space-between;
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||
align-items: center;
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||
padding: 0 96px;
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||
font-family: var(--mono);
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||
font-size: 10.5px;
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||
letter-spacing: 0.4px;
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||
color: var(--stone);
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font-variant-numeric: tabular-nums;
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z-index: 4;
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||
pointer-events: none;
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||
}
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.slide.dark .slide-foot { color: rgba(250, 249, 245, 0.74); } /* 10.5px mono on navy: keep >= AA */
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||
.slide-foot .counter {
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||
font-family: var(--mono);
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letter-spacing: 0.04em;
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||
color: var(--near-black);
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background: var(--ivory);
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padding: 4px 8px;
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border: 1px solid var(--border);
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border-radius: 2px; /* match the square hairline language of the mark */
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}
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.slide.dark .slide-foot .counter {
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color: var(--ivory);
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background: rgba(250, 249, 245, 0.08);
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border-color: rgba(250, 249, 245, 0.22);
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}
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/* ---------- progress bar ---------- */
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.deck-progress {
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position: fixed;
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left: 0; right: 0; bottom: 0;
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height: 2px;
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background: rgba(27, 54, 93, 0.08);
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z-index: 30;
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}
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.deck-progress .bar {
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height: 100%;
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background: var(--brand);
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width: 0%;
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transition: width 0.6s cubic-bezier(0.77, 0, 0.175, 1);
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}
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/* ---------- dot nav ---------- */
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#nav {
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position: fixed;
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left: 50%;
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bottom: 40px;
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transform: translateX(-50%);
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z-index: 30;
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display: flex;
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gap: 9px;
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padding: 8px 14px;
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/* flat parchment strip with a hairline, square corners: the glassy
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blurred pill was outside the kami print language */
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border-radius: 2px;
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background: rgba(245, 244, 237, 0.92);
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border: 1px solid var(--border);
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}
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#nav .dot {
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width: 7px; height: 7px;
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border-radius: 50%;
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background: rgba(27, 54, 93, 0.22);
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||
cursor: pointer;
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||
transition: background-color 0.3s cubic-bezier(0.16, 1, 0.3, 1),
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width 0.3s cubic-bezier(0.16, 1, 0.3, 1),
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transform 0.3s cubic-bezier(0.16, 1, 0.3, 1);
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||
border: 0;
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||
padding: 0;
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||
}
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#nav .dot:hover {
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background: rgba(27, 54, 93, 0.5);
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transform: scale(1.15);
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}
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#nav .dot.active {
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background: var(--brand);
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width: 22px;
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border-radius: 1px; /* active marker reads as an ink dash, not a capsule */
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}
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#hint {
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position: fixed;
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bottom: 64px; right: 28px;
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z-index: 30;
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font-family: var(--mono);
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font-size: 10px;
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letter-spacing: 0.4px;
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text-transform: uppercase;
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color: var(--stone);
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/* hint floats over both parchment and navy slides; bare stone text was
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sub-AA on the dark cover/end, so it gets the same parchment hairline
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chip language as the nav strip and counter */
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background: rgba(245, 244, 237, 0.92);
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border: 1px solid var(--border);
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border-radius: 2px;
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padding: 5px 9px;
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}
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/* ---------- COVER slide (dark) ---------- */
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/* opening beat: transform+opacity only, ease-out, staggered 0.08s.
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Scoped to the cover; the swipe track paints every slide at load, so
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animating all of them would burn the effect off-screen. */
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@keyframes kami-rise {
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from { opacity: 0; transform: translateY(18px); }
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to { opacity: 1; transform: none; }
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}
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.s-cover .slide-inner > * {
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animation: kami-rise 0.7s cubic-bezier(0.16, 1, 0.3, 1) both;
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}
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.s-cover .slide-inner > *:nth-child(2) { animation-delay: 0.08s; }
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||
.s-cover .slide-inner > *:nth-child(3) { animation-delay: 0.16s; }
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||
.s-cover .slide-inner > *:nth-child(4) { animation-delay: 0.24s; }
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.s-cover .slide-inner {
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grid-template-columns: 1fr;
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text-align: left;
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||
align-content: center;
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||
gap: 28px;
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max-width: 980px;
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}
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||
.s-cover .eyebrow {
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||
font-family: var(--sans);
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||
font-size: 12px;
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font-weight: 500;
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letter-spacing: 1.2px;
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text-transform: uppercase;
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color: rgba(250, 249, 245, 0.74); /* small caps on navy: keep >= AA */
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}
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.s-cover h1 {
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font-family: var(--serif);
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font-weight: 500;
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||
font-size: clamp(60px, 7vw, 110px);
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||
line-height: 1.05;
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||
letter-spacing: -1.2px;
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color: var(--ivory);
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||
margin: 0;
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}
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.s-cover h1 .hl { color: var(--brand-steel); }
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||
.s-cover .tagline {
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||
font-family: var(--serif);
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||
font-weight: 500;
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||
font-size: 21px;
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||
color: rgba(250, 249, 245, 0.75);
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||
max-width: 50ch;
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||
line-height: 1.45;
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}
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.s-cover .meta {
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||
margin-top: 20px;
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||
display: flex;
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||
align-items: center;
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||
flex-wrap: wrap;
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||
gap: 14px 20px;
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||
font-family: var(--mono);
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||
font-size: 11px;
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||
letter-spacing: 0.4px;
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||
text-transform: uppercase;
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||
color: rgba(250, 249, 245, 0.72); /* 11px mono on navy: keep >= AA */
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||
font-variant-numeric: tabular-nums;
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||
}
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||
.s-cover .meta .rule {
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||
width: 56px; height: 1px;
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||
background: rgba(250, 249, 245, 0.4);
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||
display: inline-block;
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||
}
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||
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||
/* ---------- CHAPTER divider (dark) ---------- */
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||
.s-chapter .slide-inner {
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||
grid-template-columns: 1fr;
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||
text-align: center;
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||
align-content: center;
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||
gap: 36px;
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||
}
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||
.s-chapter .num {
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||
font-family: var(--serif);
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||
font-weight: 500;
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||
font-size: clamp(64px, 8vw, 130px);
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||
color: rgba(250, 249, 245, 0.62); /* ghosted chapter numeral, kept >= 3:1 for large text */
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||
letter-spacing: -0.5px;
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||
line-height: 1;
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||
font-variant-numeric: tabular-nums;
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||
}
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||
.s-chapter h2 {
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||
font-family: var(--serif);
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||
font-weight: 500;
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||
font-size: clamp(48px, 5.4vw, 84px);
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||
line-height: 1.1;
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||
letter-spacing: -0.6px;
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||
color: var(--ivory);
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||
margin: 0 auto;
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||
max-width: 22ch;
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||
}
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||
.s-chapter .lede {
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||
font-family: var(--serif);
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||
font-weight: 500;
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||
font-size: 19px;
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||
color: rgba(250, 249, 245, 0.78);
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||
max-width: 42ch;
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margin: 0 auto;
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line-height: 1.5;
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}
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||
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/* ---------- CONTENT slide ---------- */
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||
.s-content .slide-inner {
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||
grid-template-columns: 1fr 2.4fr;
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||
gap: 56px;
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||
align-content: center;
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||
}
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||
.s-content.layout-full .slide-inner { grid-template-columns: 1fr; max-width: 980px; }
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||
.s-content .head { display: flex; flex-direction: column; gap: 16px; }
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||
.s-content .num {
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||
font-family: var(--serif);
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||
font-weight: 500;
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||
font-size: 14px;
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||
letter-spacing: 0.4px;
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||
color: var(--brand);
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||
font-variant-numeric: tabular-nums;
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||
}
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||
.s-content h2 {
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||
font-family: var(--serif);
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||
font-weight: 500;
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||
font-size: clamp(36px, 4vw, 56px);
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||
line-height: 1.1;
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||
letter-spacing: -0.6px;
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||
color: var(--near-black);
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||
margin: 0;
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||
max-width: 14ch;
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||
}
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||
.s-content .lede {
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||
font-family: var(--serif);
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||
font-weight: 500;
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||
font-size: 15px;
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||
color: var(--olive);
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||
max-width: 28ch;
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||
line-height: 1.5;
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||
}
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||
.s-content .body { display: flex; flex-direction: column; gap: 18px; }
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||
.s-content .body p {
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||
font-family: var(--serif);
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||
font-weight: 400;
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||
font-size: 17px;
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||
line-height: 1.55;
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||
color: var(--dark-warm);
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||
max-width: 64ch;
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||
}
|
||
.s-content .body p strong { color: var(--near-black); font-weight: 500; }
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||
.s-content .body code {
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||
font-family: var(--mono);
|
||
font-size: 14px;
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||
color: var(--brand);
|
||
background: var(--tag-08);
|
||
padding: 1px 6px;
|
||
border-radius: 3px;
|
||
}
|
||
.s-content ul.dash {
|
||
list-style: none; padding: 0; margin: 4px 0 0;
|
||
display: flex; flex-direction: column; gap: 10px;
|
||
}
|
||
.s-content ul.dash li {
|
||
position: relative; padding-left: 18px;
|
||
font-family: var(--serif);
|
||
font-weight: 400;
|
||
font-size: 16px;
|
||
line-height: 1.55;
|
||
color: var(--dark-warm);
|
||
}
|
||
.s-content ul.dash li::before {
|
||
/* hairline tick instead of a literal dash glyph (anti-slop: no -/-- in visible text) */
|
||
content: '';
|
||
position: absolute; left: 0; top: 0.72em;
|
||
width: 10px; height: 1px;
|
||
background: var(--brand);
|
||
}
|
||
.s-content .body .tag-row { margin-top: 4px; }
|
||
.s-content .tag {
|
||
display: inline-block;
|
||
font-family: var(--sans);
|
||
font-size: 12px;
|
||
font-weight: 500;
|
||
padding: 2px 8px;
|
||
border-radius: 2px;
|
||
color: var(--brand);
|
||
background: var(--tag-14);
|
||
letter-spacing: 0.4px;
|
||
}
|
||
|
||
/* ---------- STATS slide ---------- */
|
||
.s-stats .slide-inner { grid-template-columns: 1fr; gap: 48px; }
|
||
.s-stats .head { display: flex; flex-direction: column; gap: 18px; }
|
||
.s-stats .num {
|
||
font-family: var(--serif);
|
||
font-weight: 500;
|
||
font-size: 14px;
|
||
letter-spacing: 0.4px;
|
||
color: var(--brand);
|
||
font-variant-numeric: tabular-nums;
|
||
}
|
||
.s-stats h2 {
|
||
font-family: var(--serif);
|
||
font-weight: 500;
|
||
font-size: clamp(36px, 4.2vw, 60px);
|
||
line-height: 1.1;
|
||
letter-spacing: -0.6px;
|
||
color: var(--near-black);
|
||
max-width: 22ch;
|
||
margin: 0;
|
||
}
|
||
.s-stats .grid {
|
||
display: grid;
|
||
grid-template-columns: repeat(auto-fit, minmax(200px, 1fr));
|
||
gap: 0;
|
||
border-top: 1px solid var(--border);
|
||
border-bottom: 1px solid var(--border);
|
||
}
|
||
.s-stats .stat {
|
||
padding: 32px 24px 28px;
|
||
display: flex;
|
||
flex-direction: column;
|
||
gap: 8px;
|
||
border-right: 1px solid var(--border-soft);
|
||
}
|
||
.s-stats .stat:last-child { border-right: 0; }
|
||
.s-stats .stat .v {
|
||
font-family: var(--serif);
|
||
font-weight: 500;
|
||
font-size: clamp(48px, 6vw, 88px);
|
||
line-height: 1;
|
||
letter-spacing: -0.8px;
|
||
color: var(--brand);
|
||
font-variant-numeric: tabular-nums;
|
||
}
|
||
.s-stats .stat .l {
|
||
font-family: var(--serif);
|
||
font-weight: 500;
|
||
font-size: 15px;
|
||
color: var(--near-black);
|
||
margin-top: 8px;
|
||
}
|
||
.s-stats .stat .s {
|
||
font-family: var(--serif);
|
||
font-weight: 400;
|
||
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|
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</head>
|
||
<body>
|
||
|
||
<div id='deck'>
|
||
|
||
<!-- ===== 01 · COVER (dark) ===== -->
|
||
<section class='slide s-cover dark' data-slide-kind='cover'>
|
||
<div class='slide-chrome'>
|
||
<span class='left'><span class='mark'>kami</span> <b>Raman Lab</b> · Lab Meeting · Week 14</span>
|
||
<span class='right'>Gut-Sleep Cohort · Academic research</span>
|
||
</div>
|
||
<div class='slide-inner'>
|
||
<span class='eyebrow'>Lab meeting · Raman Lab · Week 14</span>
|
||
<h1>Gut microbes track <span class='hl'>deep sleep</span>, not total sleep.</h1>
|
||
<p class='tagline'>A 6-week shotgun-metagenomics cohort linking the Bacteroides:Firmicutes ratio to slow-wave sleep duration — the design, the results, and what we still can't claim.</p>
|
||
<div class='meta'>
|
||
<span>n = 64 adults · PSG subsample n = 22</span>
|
||
<span class='rule'></span>
|
||
<span>Dept. of Neuroscience · Sleep & Microbiome Lab</span>
|
||
</div>
|
||
</div>
|
||
<div class='slide-foot'>
|
||
<span>Raman Lab · MMXXVI</span>
|
||
<span class='counter'>01 / 09</span>
|
||
</div>
|
||
</section>
|
||
|
||
<!-- ===== 02 · CHAPTER (dark) ===== -->
|
||
<section class='slide s-chapter dark' data-slide-kind='chapter'>
|
||
<div class='slide-chrome'>
|
||
<span class='left'><span class='mark'>kami</span> <b>Raman Lab</b> · Lab Meeting · Week 14</span>
|
||
<span class='right'>Gut-Sleep Cohort · Academic research</span>
|
||
</div>
|
||
<div class='slide-inner'>
|
||
<p class='num'>01</p>
|
||
<h2>The field: fast-moving, still noisy.</h2>
|
||
<p class='lede'>Rodent work shows the gut-brain axis can shape sleep causally, through short-chain fatty acids and vagal afferents. Human evidence stays correlational, small-n, and inconsistent across cohorts.</p>
|
||
</div>
|
||
<div class='slide-foot'>
|
||
<span>Raman Lab · MMXXVI</span>
|
||
<span class='counter'>02 / 09</span>
|
||
</div>
|
||
</section>
|
||
|
||
<!-- ===== 03 · CONTENT ===== -->
|
||
<section class='slide s-content' data-slide-kind='content'>
|
||
<div class='slide-chrome'>
|
||
<span class='left'><span class='mark'>kami</span> <b>Raman Lab</b> · Lab Meeting · Week 14</span>
|
||
<span class='right'>Gut-Sleep Cohort · Academic research</span>
|
||
</div>
|
||
<div class='slide-inner'>
|
||
<div class='head'>
|
||
<p class='num'>01.1</p>
|
||
<h2>The gap no cohort has closed.</h2>
|
||
<p class='lede'>Most human studies measure sleep by wristband, not EEG.</p>
|
||
</div>
|
||
<div class='body'>
|
||
<p>
|
||
Prior cohorts (typically <strong>n < 30</strong>) rely on consumer-grade actigraphy, which is blind to sleep stage — it cannot tell slow-wave sleep from light sleep. None have paired <code>16S</code>-or-deeper microbiome profiling with polysomnography-grade staging in the same participants, and few control for the confounders that move both gut and sleep at once.
|
||
</p>
|
||
<ul class='dash'>
|
||
<li>Actigraphy-only designs can report "sleep quality" but not sleep architecture.</li>
|
||
<li>Diet, BMI, and antibiotic history are rarely logged as covariates.</li>
|
||
<li>No prior cohort repeated sampling across a full six-week window.</li>
|
||
</ul>
|
||
<div class='tag-row'>
|
||
<span class='tag'>Metagenomics</span>
|
||
<span class='tag'>Polysomnography</span>
|
||
<span class='tag'>Gut-brain axis</span>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<div class='slide-foot'>
|
||
<span>Raman Lab · MMXXVI</span>
|
||
<span class='counter'>03 / 09</span>
|
||
</div>
|
||
</section>
|
||
|
||
<!-- ===== 04 · CONTENT ===== -->
|
||
<section class='slide s-content' data-slide-kind='content'>
|
||
<div class='slide-chrome'>
|
||
<span class='left'><span class='mark'>kami</span> <b>Raman Lab</b> · Lab Meeting · Week 14</span>
|
||
<span class='right'>Gut-Sleep Cohort · Academic research</span>
|
||
</div>
|
||
<div class='slide-inner'>
|
||
<div class='head'>
|
||
<p class='num'>01.2</p>
|
||
<h2>Design: what we actually ran.</h2>
|
||
<p class='lede'>Six weeks, 64 adults, a polysomnography subsample.</p>
|
||
</div>
|
||
<div class='body'>
|
||
<p>
|
||
Stool samples were collected at week 0 and week 6 and run through shotgun metagenomic sequencing. All 64 participants wore actigraphy nightly; a <strong>22-person subsample also underwent overnight polysomnography</strong> at both timepoints, giving us gold-standard sleep staging alongside microbial composition.
|
||
</p>
|
||
<p>
|
||
Diet was logged by 3-day food record each week. Linear mixed-effects models carry participant as a random intercept and adjust for BMI, dietary fiber intake, and antibiotic use in the prior 90 days.
|
||
</p>
|
||
<ul class='dash'>
|
||
<li>Week 0 & week 6 stool sampling, shotgun metagenomics (Illumina NovaSeq).</li>
|
||
<li>Nightly actigraphy, all 64; overnight PSG on a 22-person subsample.</li>
|
||
<li>LME models adjust for BMI, fiber intake, and 90-day antibiotic history.</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
<div class='slide-foot'>
|
||
<span>Raman Lab · MMXXVI</span>
|
||
<span class='counter'>04 / 09</span>
|
||
</div>
|
||
</section>
|
||
|
||
<!-- ===== 05 · STATS ===== -->
|
||
<section class='slide s-stats' data-slide-kind='stats'>
|
||
<div class='slide-chrome'>
|
||
<span class='left'><span class='mark'>kami</span> <b>Raman Lab</b> · Lab Meeting · Week 14</span>
|
||
<span class='right'>Gut-Sleep Cohort · Academic research</span>
|
||
</div>
|
||
<div class='slide-inner'>
|
||
<div class='head'>
|
||
<p class='num'>01.3</p>
|
||
<h2>What moved, and what didn't.</h2>
|
||
</div>
|
||
<div class='grid'>
|
||
<div class='stat'>
|
||
<div class='v'>+18min</div>
|
||
<div class='l'>Slow-wave sleep</div>
|
||
<div class='s'>per SD increase in Bacteroides:Firmicutes ratio, PSG subsample.</div>
|
||
</div>
|
||
<div class='stat'>
|
||
<div class='v'>r=0.41</div>
|
||
<div class='l'>SCFA – SWS correlation</div>
|
||
<div class='s'>fecal butyrate vs. slow-wave minutes, FDR q < 0.05.</div>
|
||
</div>
|
||
<div class='stat'>
|
||
<div class='v'>n.s.</div>
|
||
<div class='l'>Total sleep time</div>
|
||
<div class='s'>no association with any measured microbial ratio, p = 0.61.</div>
|
||
</div>
|
||
<div class='stat'>
|
||
<div class='v'>22/64</div>
|
||
<div class='l'>PSG subsample</div>
|
||
<div class='s'>gold-standard staging; remainder actigraphy-only.</div>
|
||
</div>
|
||
</div>
|
||
<p class='caption'>Raman Lab · shotgun metagenomics + PSG cohort · preprint in preparation · MMXXVI</p>
|
||
</div>
|
||
<div class='slide-foot'>
|
||
<span>Raman Lab · MMXXVI</span>
|
||
<span class='counter'>05 / 09</span>
|
||
</div>
|
||
</section>
|
||
|
||
<!-- ===== 06 · CHAPTER (dark) ===== -->
|
||
<section class='slide s-chapter dark' data-slide-kind='chapter'>
|
||
<div class='slide-chrome'>
|
||
<span class='left'><span class='mark'>kami</span> <b>Raman Lab</b> · Lab Meeting · Week 14</span>
|
||
<span class='right'>Gut-Sleep Cohort · Academic research</span>
|
||
</div>
|
||
<div class='slide-inner'>
|
||
<p class='num'>02</p>
|
||
<h2>The claim we can actually make.</h2>
|
||
<p class='lede'>Gut composition tracks sleep architecture — slow-wave depth — not sleep quantity. A distinction prior actigraphy-only studies could never see.</p>
|
||
</div>
|
||
<div class='slide-foot'>
|
||
<span>Raman Lab · MMXXVI</span>
|
||
<span class='counter'>06 / 09</span>
|
||
</div>
|
||
</section>
|
||
|
||
<!-- ===== 07 · QUOTE ===== -->
|
||
<section class='slide s-quote' data-slide-kind='quote'>
|
||
<div class='slide-chrome'>
|
||
<span class='left'><span class='mark'>kami</span> <b>Raman Lab</b> · Lab Meeting · Week 14</span>
|
||
<span class='right'>Gut-Sleep Cohort · Academic research</span>
|
||
</div>
|
||
<div class='slide-inner'>
|
||
<blockquote>
|
||
A correlation this size, in a subsample this small, does not tell us the microbiome causes deeper sleep. It tells us exactly where to point a causal experiment next.
|
||
</blockquote>
|
||
<div class='author'>
|
||
<span class='glyph'>e</span>
|
||
<p>
|
||
Dr. Elena Cho
|
||
<span>Principal Investigator · Sleep & Microbiome Lab</span>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
<div class='slide-foot'>
|
||
<span>Raman Lab · MMXXVI</span>
|
||
<span class='counter'>07 / 09</span>
|
||
</div>
|
||
</section>
|
||
|
||
<!-- ===== 08 · CTA ===== -->
|
||
<section class='slide s-cta' data-slide-kind='cta'>
|
||
<div class='slide-chrome'>
|
||
<span class='left'><span class='mark'>kami</span> <b>Raman Lab</b> · Lab Meeting · Week 14</span>
|
||
<span class='right'>Gut-Sleep Cohort · Academic research</span>
|
||
</div>
|
||
<div class='slide-inner'>
|
||
<span class='eyebrow'>Next in the pipeline</span>
|
||
<h2>Can we move the ratio — and does sleep follow?</h2>
|
||
<p class='body'>
|
||
Proposed follow-up: a 4-week fiber-supplementation crossover trial (n = 40, PSG on every participant) testing whether raising the Bacteroides:Firmicutes ratio causally increases slow-wave sleep. IRB submission targeted for Q3.
|
||
</p>
|
||
<div class='actions'>
|
||
<a class='btn btn-primary' href='#'>Review the IRB draft</a>
|
||
<a class='btn btn-ghost' href='#'>See the full dataset</a>
|
||
</div>
|
||
</div>
|
||
<div class='slide-foot'>
|
||
<span>Raman Lab · MMXXVI</span>
|
||
<span class='counter'>08 / 09</span>
|
||
</div>
|
||
</section>
|
||
|
||
<!-- ===== 09 · END (dark) ===== -->
|
||
<section class='slide s-end dark' data-slide-kind='end'>
|
||
<div class='slide-chrome'>
|
||
<span class='left'><span class='mark'>kami</span> <b>Raman Lab</b> · Lab Meeting · Week 14</span>
|
||
<span class='right'>Gut-Sleep Cohort · Academic research</span>
|
||
</div>
|
||
<div class='slide-inner'>
|
||
<div class='word'>Sleep, <span class='hl'>deeper.</span></div>
|
||
<p class='colophon'>Raman Lab · Dept. of Neuroscience · MMXXVI · Preprint in preparation · Lab meeting Nº 14</p>
|
||
</div>
|
||
<div class='slide-foot'>
|
||
<span>Raman Lab · MMXXVI</span>
|
||
<span class='counter'>09 / 09</span>
|
||
</div>
|
||
</section>
|
||
|
||
</div>
|
||
|
||
<div id='nav'></div>
|
||
<div id='hint'>← / → · esc · swipe</div>
|
||
<div class='deck-progress'><div class='bar'></div></div>
|
||
|
||
<script>
|
||
(function () {
|
||
var deck = document.getElementById('deck');
|
||
if (!deck) return;
|
||
var slides = Array.prototype.slice.call(deck.querySelectorAll('.slide'));
|
||
var nav = document.getElementById('nav');
|
||
var bar = document.querySelector('.deck-progress .bar');
|
||
var total = slides.length;
|
||
var idx = 0, lock = false;
|
||
|
||
deck.style.width = (total * 100) + 'vw';
|
||
|
||
slides.forEach(function (s, i) {
|
||
var b = document.createElement('button');
|
||
b.className = 'dot';
|
||
b.dataset.i = i;
|
||
b.setAttribute('aria-label', 'Slide ' + (i + 1));
|
||
b.onclick = function () { go(i); };
|
||
nav.appendChild(b);
|
||
});
|
||
|
||
/* Unthrottled state update. The interaction throttle (`lock`) only
|
||
guards wheel/key/touch so a fast input burst doesn't overshoot the
|
||
transition; host- and observer-driven sync must bypass it, otherwise
|
||
a host message or restoreInitialSlide that lands inside the 700ms
|
||
window after go(0) silently no-ops and the deck stays on slide 1
|
||
while the host counter advances. */
|
||
function applySlide(n) {
|
||
idx = Math.max(0, Math.min(total - 1, n));
|
||
deck.style.transform = 'translateX(' + (-idx * 100) + 'vw)';
|
||
/* load-bearing: .slide.active is read by Open Design's host bridge
|
||
(src/runtime/srcdoc.ts findActiveByClass) to drive the slide
|
||
counter. No CSS targets it — do not remove. */
|
||
slides.forEach(function (s, i) { s.classList.toggle('active', i === idx); });
|
||
nav.querySelectorAll('.dot').forEach(function (d, i) {
|
||
d.classList.toggle('active', i === idx);
|
||
});
|
||
if (bar) bar.style.width = (((idx + 1) / total) * 100) + '%';
|
||
}
|
||
|
||
function go(n) {
|
||
if (lock) return;
|
||
applySlide(n);
|
||
lock = true;
|
||
setTimeout(function () { lock = false; }, 700);
|
||
}
|
||
|
||
/* ESC overview */
|
||
var overviewOn = false;
|
||
var ov = document.createElement('div');
|
||
ov.id = 'overview';
|
||
document.body.appendChild(ov);
|
||
|
||
function buildOverview() {
|
||
ov.innerHTML = '';
|
||
var head = document.createElement('div');
|
||
head.className = 'ov-head';
|
||
head.innerHTML = '<span><b>Slide overview</b> · esc to close</span><span>' +
|
||
String(idx + 1).padStart(2, '0') + ' / ' + String(total).padStart(2, '0') + '</span>';
|
||
ov.appendChild(head);
|
||
var grid = document.createElement('div');
|
||
grid.className = 'ov-grid';
|
||
slides.forEach(function (s, i) {
|
||
var card = document.createElement('div');
|
||
card.className = 'ov-card' + (i === idx ? ' active' : '');
|
||
var thumb = document.createElement('div');
|
||
thumb.className = 'ov-thumb';
|
||
var clone = s.cloneNode(true);
|
||
clone.className = clone.className + ' clone';
|
||
clone.style.transform = 'scale(0.18)';
|
||
thumb.appendChild(clone);
|
||
var label = document.createElement('div');
|
||
label.className = 'ov-label';
|
||
label.innerHTML = '<b>' + String(i + 1).padStart(2, '0') + '</b><span>' +
|
||
(s.dataset.slideKind || '') + '</span>';
|
||
card.appendChild(thumb);
|
||
card.appendChild(label);
|
||
card.onclick = function () { toggleOverview(); go(i); };
|
||
grid.appendChild(card);
|
||
});
|
||
ov.appendChild(grid);
|
||
}
|
||
|
||
function toggleOverview() {
|
||
overviewOn = !overviewOn;
|
||
if (overviewOn) { buildOverview(); ov.style.display = 'block'; }
|
||
else { ov.style.display = 'none'; }
|
||
}
|
||
|
||
addEventListener('keydown', function (e) {
|
||
if (e.key === 'Escape') { e.preventDefault(); toggleOverview(); return; }
|
||
if (overviewOn) return;
|
||
if (e.key === 'ArrowRight' || e.key === 'PageDown' || e.key === ' ' || e.key === 'ArrowDown') {
|
||
e.preventDefault(); go(idx + 1);
|
||
} else if (e.key === 'ArrowLeft' || e.key === 'PageUp' || e.key === 'ArrowUp') {
|
||
e.preventDefault(); go(idx - 1);
|
||
} else if (e.key === 'Home') {
|
||
e.preventDefault(); go(0);
|
||
} else if (e.key === 'End') {
|
||
e.preventDefault(); go(total - 1);
|
||
}
|
||
});
|
||
|
||
var wheelTO = null, wheelAcc = 0;
|
||
addEventListener('wheel', function (e) {
|
||
if (overviewOn) return;
|
||
wheelAcc += e.deltaY + e.deltaX;
|
||
if (Math.abs(wheelAcc) > 60) {
|
||
go(idx + (wheelAcc > 0 ? 1 : -1));
|
||
wheelAcc = 0;
|
||
}
|
||
clearTimeout(wheelTO);
|
||
wheelTO = setTimeout(function () { wheelAcc = 0; }, 150);
|
||
}, { passive: true });
|
||
|
||
var tx = 0, ty = 0;
|
||
addEventListener('touchstart', function (e) {
|
||
tx = e.touches[0].clientX; ty = e.touches[0].clientY;
|
||
}, { passive: true });
|
||
addEventListener('touchend', function (e) {
|
||
if (overviewOn) return;
|
||
var dx = e.changedTouches[0].clientX - tx;
|
||
var dy = e.changedTouches[0].clientY - ty;
|
||
if (Math.abs(dx) > 50 && Math.abs(dx) > Math.abs(dy)) {
|
||
go(idx + (dx < 0 ? 1 : -1));
|
||
}
|
||
}, { passive: true });
|
||
|
||
/* Host-driven navigation: Open Design's host bridge classifies this deck
|
||
as class-driven (because go() toggles .slide.active) but the visible
|
||
slide is moved by deck.style.transform, which the bridge can't drive.
|
||
Two cooperating handlers keep the deck in sync with the host:
|
||
1. An od:slide message listener routes host nav through go() and
|
||
calls stopImmediatePropagation() so the bridge's own listener
|
||
(registered after this one) doesn't run a second time and
|
||
overshoot by re-reading the freshly-toggled .active class.
|
||
2. A MutationObserver on each slide watches .active and pulls the
|
||
deck transform onto the active index for class changes that
|
||
don't come through a message — chiefly the bridge's
|
||
restoreInitialSlide path, which calls setActive() directly. */
|
||
addEventListener('message', function (e) {
|
||
var data = e && e.data;
|
||
if (!data || data.type !== 'od:slide') return;
|
||
if (typeof e.stopImmediatePropagation === 'function') e.stopImmediatePropagation();
|
||
if (data.action === 'go' && typeof data.index === 'number') applySlide(data.index);
|
||
else if (data.action === 'next') applySlide(idx + 1);
|
||
else if (data.action === 'prev') applySlide(idx - 1);
|
||
else if (data.action === 'first') applySlide(0);
|
||
else if (data.action === 'last') applySlide(total - 1);
|
||
});
|
||
|
||
if (typeof MutationObserver !== 'undefined') {
|
||
var syncFromActiveClass = function () {
|
||
for (var i = 0; i < slides.length; i++) {
|
||
if (slides[i].classList && slides[i].classList.contains('active') && i !== idx) {
|
||
applySlide(i);
|
||
return;
|
||
}
|
||
}
|
||
};
|
||
var mo = new MutationObserver(syncFromActiveClass);
|
||
slides.forEach(function (s) { mo.observe(s, { attributes: true, attributeFilter: ['class'] }); });
|
||
}
|
||
|
||
applySlide(0);
|
||
})();
|
||
</script>
|
||
|
||
</body>
|
||
</html>
|