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1supplementalt nameevidence level - score. 0 = no evidence, 1,2 = slight, 3 = conflicting , 4 = promising, 5 = good, 6 = strong Claimed improved aspect of fitnessfitness categorysport or exercise type testedOTWpopularitynumber of studies examinednumber of citationsefficacynotesexcludeCochrane systematic reviewOther International review board or metastudyno. of studies in Cochrane metastudyno. of studies in metastudyyear(s) of metastudyNo. of individual studies / reviewsN positive studies / trials% positive studies/ trialsmain study sourceLink to main individual studyLink to individual studyLink to individual studyLink to individual studyLink to individual studyLink to individual studyLink to individual studyLink to individual studyLink to individual studyLink to individual studyLink to individual studyLink to individual studyLink to individual studyLink to individual studyLink to individual studyLink to individual studyLink to individual studyLink to individual studyLink to individual studyLink to individual studyLink to individual studyLink to individual study
2AAKGL-arginine alpha-ketoglutarate1peak power outputstrength–powerweight trainingOTW242120A 2006 study found AAKG supplementation improved maximum effort 1-repetition bench press and Wingate peak power performance.0000-11100.00%Campbell et al (2006)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/549/CN-00668549/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/549/CN-00668549/frame.html
3AAKGL-arginine alpha-ketoglutarate0body composition, aerobic capacity, muscle endurancefat burning–muscle building, aerobic–enduranceweight training2421200000-100.00%Campbell et al (2006)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/549/CN-00668549/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/549/CN-00668549/frame.html
4Baking sodaBicarbonate of soda, sodium bicarbonate, NaHCO35high-intensity performanceanaerobic–high-intensityrowing, cycling, swimming, running, other94714140Gulping down baking soda (sodium bicarbonate) makes the blood more alkaline, improving performance in lactic-acid-fueled events like the 800m sprint. Downside: a badly upset stomach.0000-14964.29%Siegler et al (2010)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/219/CN-00770219/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/778/CN-00759778/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/004/CN-00749004/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/229/CN-00760229/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/219/CN-00770219/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/656/CN-00733656/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/708/CN-00772708/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/130/CN-00762130/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/160/CN-00701160/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/159/CN-00701159/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/622/CN-00572622/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/402/CN-00564402/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/818/CN-00559818/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/017/CN-00559017/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/648/CN-00408648/frame.html
5BCAAsbranched-chain amino acids, leucine, isoleucine, valine4fatigue resistanceaerobic–endurancecycling, circuit training54903660Branched-chain amino acids0000-33100.00%Greer et al (2011)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/959/CN-00781959/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/959/CN-00781959/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/239/CN-00787239/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/438/CN-00554438/frame.html
6BCAAsbranched-chain amino acids, leucine, isoleucine, valine3aerobic performance, endurance, poweraerobic–endurance, strength–powercycling, other54904660Branched-chain amino acids0000-4250.00%Matsumoto et al (2009)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/665/CN-00705665/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/959/CN-00781959/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/665/CN-00705665/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/412/CN-00561412/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/174/CN-00560174/frame.html
7BCAAsbranched-chain amino acids, leucine, isoleucine, valine1immune defences in athletesgeneral fitnessrunning, otherOTW54902660Branched-chain amino acids0000-22100.00%Bassit et al (2002)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/021/CN-00389021/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/021/CN-00389021/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/262/CN-00372262/frame.html
8BCAAsbranched-chain amino acids, leucine, isoleucine, valine0body compositionfat burning–muscle buildingswimming, rowing54901660Branched-chain amino acids0000-100.00%Tang (2003)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/245/CN-00474245/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/245/CN-00474245/frame.html
9BCAAsbranched-chain amino acids, leucine, isoleucine, valine6muscle damage + sorenessrecovery–injury preventionweight training, circuit training, cycling, swimming54907660Taking branched-chain amino acids before exercise can reduce damage to muscle tissue and soreness caused by training (and overtraining). 0000-77100.00%Shimomura et al (2010)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/776/CN-00759776/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/773/CN-00751773/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/776/CN-00759776/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/009/CN-00629009/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/808/CN-00565808/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/438/CN-00554438/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/613/CN-00442613/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/649/CN-00441649/frame.html
10Beetroot juice4aerobic efficiencyaerobic–endurancerunning, cycling26745The nitrates in beetroot juice improve time to exhaustion and various measures of oxygen consumption during aerobic exercise, also reducing resting blood pressure. Downsides: purple pee.0000-44100.00%Lansley et al (2011)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/843/CN-00800843/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/843/CN-00800843/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/096/CN-00787096/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/367/CN-00760367/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/472/CN-00733472/frame.html
11Beta alanine1high-intensity performanceaerobic–endurance, anaerobic–high-intensityrowing, cycling, running92042840000-4125.00%Walter et al (2010)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/456/CN-00750456/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/549/CN-00781549/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/456/CN-00750456/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/381/CN-00697381/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/957/CN-00626957/frame.html
12Beta alanine2training tolerance, fatiguerecovery–injury prevention, sports psychologyrunning, otherOTW92022840000-22100.00%Hoffman et al (2008a)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/702/CN-00686702/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/702/CN-00686702/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/381/CN-00697381/frame.html
13Beta alanine1muscular endurance, powerstrength–power, anaerobic–high-intensityweight trainingOTW92012840000-11100.00%Hoffman et al (2008b)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/829/CN-00686829/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/829/CN-00686829/frame.html
14Betaine1exercise tolerance in hot conditionsgeneral fitnessrunningOTW104011620000-11100.00%Armstrong et al (2008)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/208/CN-00639208/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/208/CN-00639208/frame.html
15Betaine0sprint performanceanaerobic–high-intensityrunning104011620000-100.00%Armstrong et al (2008)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/208/CN-00639208/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/208/CN-00639208/frame.html
16Bitter orangeCitrus aurantium, sour orange, p-synephrine, synephrine, octopamine (active ingredients)0weight lossfat burning–muscle buildingother40631680Bitter orange may raise resting metabolic rate – burning more calories – and possibly also heart rate and blood pressure. However, commercial preparations normally contain caffeine too and effects can be difficult to untangle.01012004200.00%Review: Bent et al (2004)http://onlinelibrary.wiley.com/o/cochrane/cldare/articles/DARE-12004006974/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/cldare/articles/DARE-12004006974/frame.htmlhttp://www.ncbi.nlm.nih.gov/pubmed/15337824http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/539/CN-00577539/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/240/CN-00524240/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/964/CN-00424964/frame.html
17Bovine colostrum2high intensity performance, enduranceaerobic–endurancecycling, running, rowing, other16551940000-5360.00%Shing et al (2006)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/365/CN-00566365/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/365/CN-00566365/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/579/CN-00409579/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/364/CN-00390364/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/378/CN-00411378/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/427/CN-00412427/frame.html
18Bovine colostrum1immune defences in athletesgeneral fitnessswimming, cycling16531940000-3133.33%Carol et al (2011)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/582/CN-00788582/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/582/CN-00788582/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/582/CN-00788582/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/165/CN-00586165/frame.html
19Bovine colostrum1muscle gainfat burning–muscle buildingweight trainingOTW16511940000-11100.00%Antonio et al (2001)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/368/CN-00347368/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/368/CN-00347368/frame.html
20Bovine colostrum1strength, power, sprint performancestrength–power, anaerobic–high-intensityweight training, cycling, other16531940000-3266.67%Mero et al (2005)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/462/CN-00551462/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/462/CN-00551462/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/068/CN-00439068/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/427/CN-00412427/frame.html
21Caffeine4intense aerobic performanceaerobic–endurancecycling, rowing725074090000-7571.43%Jenkins et al (2008)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/134/CN-00649134/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/753/CN-00741753/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/134/CN-00649134/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/214/CN-00667214/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/711/CN-00501711/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/180/CN-00426180/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/581/CN-00372581/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/600/CN-00346600/frame.html
22Caffeine5endurance performanceaerobic–endurancecycling, running7250154090000-151066.67%Irwin et al (2011)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/557/CN-00787557/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/557/CN-00787557/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/769/CN-00769769/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/515/CN-00733515/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/429/CN-00785429/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/856/CN-00697856/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/878/CN-00684878/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/808/CN-00562808/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/308/CN-00529308/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/587/CN-00512587/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/642/CN-00504642/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/753/CN-00435753/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/305/CN-00457305/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/426/CN-00412426/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/977/CN-00425977/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/044/CN-00410044/frame.html
23Caffeine3skill, agility + speedsports psychologyfootball, cycling, running, other72506409Caffeine may improve footballers' passing accuracy, but reaction time and coordination tests show negligible benefit over placebo. One study found caffeined-up soldiers fired more shots more quickly, but were no better at telling the enemy apart.0000-6350.00%Lorino et al (2006)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/725/CN-00574725/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/486/CN-00722486/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/916/CN-00668916/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/270/CN-00683270/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/725/CN-00574725/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/308/CN-00529308/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/314/CN-00560314/frame.html
24Caffeine4performance when sleep-deprivedsports psychologyother72503409Sleep-deprived soldiers given caffeine showed better performance in obstacle running, marksmanship, vigilance tests and simulated driving tasks than those who went without.0000-33100.00%McLellan et al (2007)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/196/CN-00612196/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/196/CN-00612196/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/453/CN-00511453/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/938/CN-00371938/frame.html
25Caffeine6mood during exercisesports psychologyweight training, cycling, other725011409Old news: caffeine boosts mood and reduces perceived exertion during exercise, keeping you motivated. Downsides: anxiety and palpitations at high doses or in the caffeine-sensitive.0000-11981.82%Backhouse et al (2011)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/805/CN-00799805/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/805/CN-00799805/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/502/CN-00778502/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/384/CN-00780384/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/435/CN-00697435/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/437/CN-00639437/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/287/CN-00588287/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/659/CN-00578659/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/002/CN-00571002/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/711/CN-00501711/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/884/CN-00559884/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/975/CN-00458975/frame.html
26Caffeine3high-intensity performanceanaerobic–high-intensityweight training, cycling, running7250144090000-14857.14%Astorino et al (2010)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/696/CN-00786696/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/763/CN-00801763/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/384/CN-00780384/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/753/CN-00741753/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/696/CN-00786696/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/630/CN-00718630/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/144/CN-00638144/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/299/CN-00687299/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/214/CN-00667214/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/954/CN-00576954/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/063/CN-00575063/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/970/CN-00777970/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/646/CN-00785646/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/270/CN-00683270/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/723/CN-00349723/frame.html
27Calcium pyruvate0body composition, metabolismfat burning–muscle building, general fitnessother5711520000-100.00%Koh-Banerjee et al (2005)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/267/CN-00521267/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/267/CN-00521267/frame.html
28CaseinCasein hydrolysate5muscle building, endurance, strengthfat burning–muscle building, strength–power, aerobic–endurancecycling, weight training2380540Like whey, casein is a kind of protein found in milk. Some studies have found it to be as effective as whey at muscle building when taken after weight training. 0000-55100.00%Reitelseder et al (2011)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/142/CN-00772142/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/142/CN-00772142/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/820/CN-00718820/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/987/CN-00516987/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/190/CN-00297190/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/770/CN-00702770/frame.html
29ChitosanGymnema sylvestre1weight + fat loss, cholesterolfat burning–muscle buildingotherOTW983154Cochrane review: chitosan is more effective than placebo for short-term weight loss, but many studies are poor quality. Results from high quality trials only suggest minimal effect.1015020080--Cochrane Review: Jull et al (2008)http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003892.pub3/abstracthttp://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003892.pub3/abstract
30Chromium Chromium picolinate0.5high-intensity fitness, weight + fat loss, strengthfat burning–muscle building, aerobic–endurance, anaerobic–high-intensity, strength–powerweight training, running4140101220Chromium is often used by diabetic people to lower blood sugar but there's no evidence of any ergogenic benefit and only weak evidence it can aid weight loss. 0101020031000.00%Review: Pittler et al (2003)http://onlinelibrary.wiley.com/o/cochrane/cldare/articles/DARE-12003000871/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/596/CN-00742596/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/531/CN-00698531/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/832/CN-00586832/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/585/CN-00409585/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/543/CN-00373543/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/374/CN-00456374/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/029/CN-00278029/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/601/CN-00346601/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/585/CN-00409585/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/374/CN-00456374/frame.html
31CLAConjugated linoleic acid4body compositionfat burning–muscle buildingother362011374May help obese people lose fat and gain muscle. Downsides: may also increase markers of inflammation in the short term.0000-11654.55%Steck et al (2007)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/134/CN-00588134/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/905/CN-00799905/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/890/CN-00803890/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/749/CN-00762749/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/134/CN-00588134/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/872/CN-00586872/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/834/CN-00617834/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/671/CN-00578671/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/998/CN-00576998/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/237/CN-00469237/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/415/CN-00408415/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/973/CN-00325973/frame.html
32CLAConjugated linoleic acid0enduranceaerobic–enduranceother362013740000-100.00%Colakoglu et al (2006)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/998/CN-00576998/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/998/CN-00576998/frame.html
33Cordyceps sinensisCordymax Cs4, Cs-41endurance performance, aerobic capacityaerobic–endurancecyclingOTW1070270000-2150.00%Chen et al (2010)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/044/CN-00769044/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/044/CN-00769044/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/443/CN-00468443/frame.html
34CreatineCreatine monohydrate (sometimes creatine pyruvate or citrate)2aerobic enduranceaerobic–endurancecycling, rowing, running1590350900000-3266.67%Murphy et al (2005)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/443/CN-00531443/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/443/CN-00531443/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/200/CN-00440200/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/651/CN-00377651/frame.html
35CreatineCreatine monohydrate (sometimes creatine pyruvate or citrate)3high-intensity performanceanaerobic–high-intensityrunning, cycling, circuit training, rowing, other15901150900000-11545.45%Fukuda et al (2010)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/122/CN-00762122/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/122/CN-00762122/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/509/CN-00734509/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/972/CN-00587972/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/957/CN-00563957/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/821/CN-00488821/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/200/CN-00440200/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/060/CN-00559060/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/915/CN-00518915/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/751/CN-00377751/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/872/CN-00377872/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/362/CN-00425362/frame.html
36CreatineCreatine monohydrate (sometimes creatine pyruvate or citrate)0muscle damage + recoveryrecovery–injury preventionweight training1590250900000-200.00%Rawson et al (2007)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/432/CN-00647432/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/432/CN-00647432/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/461/CN-00375461/frame.html
37CreatineCreatine monohydrate (sometimes creatine pyruvate or citrate)5strength, power, neuromuscular functionstrength–powerweight training, other15901950900000-191263.16%Kurosawa et al (2003)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/620/CN-00558620/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/491/CN-00743491/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/637/CN-00813637/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/970/CN-00648970/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/016/CN-00642016/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/481/CN-00571481/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/998/CN-00521998/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/357/CN-00562357/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/312/CN-00435312/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/620/CN-00558620/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/578/CN-00422578/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/878/CN-00474878/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/762/CN-00472762/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/158/CN-00436158/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/651/CN-00377651/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/009/CN-00377009/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/168/CN-00376168/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/872/CN-00377872/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/857/CN-00371857/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/289/CN-00372289/frame.html
38CreatineCreatine monohydrate (sometimes creatine pyruvate or citrate)5muscle massfat burning–muscle buildingweight training, rowing1590125090Creatine helps you bulk up. Downsides: weight gain (if that's not what you want), it's expensive and some studies suggest it works better in men than women.0000-12975.00%Chilibeck et al (2004)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/754/CN-00503754/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/754/CN-00503754/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/491/CN-00743491/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/016/CN-00642016/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/821/CN-00488821/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/578/CN-00422578/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/878/CN-00474878/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/915/CN-00518915/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/762/CN-00472762/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/158/CN-00436158/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/168/CN-00376168/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/872/CN-00377872/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/520/CN-00275520/frame.html
39Creatine pyruvate0repeated sprint performanceaerobic–endurancecycling2451180000-100.00%Van Schuylenbergh et al (2003)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/260/CN-00436260/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/260/CN-00436260/frame.html
40DHEADehydroepiandrosterone, 7-DHEA1strength + muscle mass in the elderlygeneral fitness, strength–power, fat burning–muscle buildingweight training, otherOTW38202601DHEA combined with exercise – such as weight training, yoga or chair aerobics – can improve muscle strength and function in elderly people. 0000-22100.00%Kenny et al (2010)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/558/CN-00760558/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/558/CN-00760558/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/836/CN-00570836/frame.html
41DHEADehydroepiandrosterone, 7-DHEA0general fitness in older adultsgeneral fitnessweight training, other382026010000-200.00%Igwebuike et al (2008)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/464/CN-00628464/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/464/CN-00628464/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/461/CN-00374461/frame.html
42Fish oilomega 3 PUFAs0metabolismgeneral fitnesscycling10800130900000-100.00%Bortolotti et al (2007)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/722/CN-00586722/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/722/CN-00586722/frame.html
43Fish oilomega 3 PUFAs3cardio fitness markersgeneral fitnessfootball, cycling1080043090Omega-3-rich fish oil can improve heart function, lower cardio risk factors, lower heart rate and oxygen consumption and improve heart rate variability during exercise.0000-44100.00%Peoples et al (2008)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/761/CN-00668761/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/487/CN-00733487/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/761/CN-00668761/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/848/CN-00647848/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/706/CN-00588706/frame.html
44Fish oilomega 3 PUFAs0enduranceaerobic–endurancefootball, cycling10800330900000-300.00%Buckley et al (2009)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/487/CN-00733487/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/487/CN-00733487/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/406/CN-00732406/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/761/CN-00668761/frame.html
45Fish oilomega 3 PUFAs1body fatfat burning–muscle buildingotherOTW1080013090A 2007 study of overweight adults found 12 weeks of fish oil alone reduced body fat, but subjects lost more fat when fish oil was combined with walking exercise.0000-11100.00%Hill et al (2007)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/706/CN-00588706/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/706/CN-00588706/frame.html
46Fish oilomega 3 PUFAs2inflammation + muscle sorenessrecovery–injury preventionweight training, cycling, swimming1080063090Although commonly believed to lower inflammation, evidence for fish oil's anti-inflammatory effect during or after exercise is weak. 0000-6233.33%Andrade et al (2007)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/010/CN-00620010/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/821/CN-00443821/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/406/CN-00732406/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/010/CN-00620010/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/406/CN-00732406/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/646/CN-00451646/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/573/CN-00330573/frame.html
47ForskolinColeus Forskohlii1weight loss in overweight menfat burning–muscle buildingotherOTW2861130000-11100.00%Godard et al (2005)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/808/CN-00529808/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/808/CN-00529808/frame.html
48Glutamine0strength, muscle massstrength–power, fat burning–muscle buildingweight training, other3610317200000-300.00%Candow et al (2001)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/433/CN-00388433/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/433/CN-00388433/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/952/CN-00576952/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/754/CN-00377754/frame.html
49Glycerol1enduranceaerobic–enduranceotherOTW851199May improve performance in endurance sports by enhancing water retention, but more research is needed.010? full paper not available20071--Review: Goulet et al (2007)http://onlinelibrary.wiley.com/o/cochrane/cldare/articles/DARE-12007009325/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/cldare/articles/DARE-12007009325/frame.html
50GP L-CarnitineGlycine propionyl-L-carnitine, L-carnitine L-tartrate1metabolism, fitness markersfat burning–muscle building, general fitnessotherOTW310213000000-20.525.00%Bloomer et al (2009)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/504/CN-00742504/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/183/CN-00761183/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/504/CN-00742504/frame.html
51GP L-CarnitineGlycine propionyl-L-carnitine, L-carnitine L-tartrate0aerobic + anaerobic performanceaerobic–endurance, anaerobic-high-intensityother310113000000-100.00%Smith et al (2008)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/080/CN-00630080/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/080/CN-00630080/frame.html
52Green tea extractCatechins0enduranceaerobic–endurancecycling29902380000-200.00%Eichenberger et al (2010)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/171/CN-00749171/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/171/CN-00749171/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/082/CN-00734082/frame.html
53Green tea extractCatechins3fat burning, oxidative stress reductionfat burning–muscle building, recovery–injury preventioncycling, weight training2990538In combination with regular aerobic exercise, the catechins and polyphenols in green tea may enhance metabolism of fat – especially abdominal fat – and reduce oxidative stress, which can contribute to injury.0000-53.570.00%Eichenberger et al (2009)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/692/CN-00722692/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/692/CN-00722692/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/447/CN-00813447/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/720/CN-00668720/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/082/CN-00734082/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/306/CN-00638306/frame.html
54HCAGarcinia cambogi, (-)-Hydroxycitrate3fat burningfat burning–muscle buildingcycling675454Studies of HCA found it increased fat burning during exercise and prevented new fat cells from forming, even when the experimental subjects overate.0000-4375.00%Kovacs and Westerterp-Plantenga (2006) http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/560/CN-00565560/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/560/CN-00565560/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/635/CN-00457635/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/431/CN-00409431/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/518/CN-00384518/frame.html
55HCAGarcinia cambogi, (-)-Hydroxycitrate1enduranceaerobic–endurancecyclingOTW675254May fire up fat metabolism, sparing carbohydrate fuel and allowing you to exercise for longer before getting exhausted.0000-22100.00%Lim et al (2003)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/635/CN-00457635/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/635/CN-00457635/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/431/CN-00409431/frame.html
56HMBβ-Hydroxy-β-Methylbutyrate3strengthstrength–powerweight training8094327A 2009 meta-analysis of 9 studies found HMB plus weight training caused small leg strength gains in untrained men but not trained weightlifters. 030920091--Meta-analysis: Rowlands and Thomson (2009)http://www.ncbi.nlm.nih.gov/pubmed/19387395http://www.ncbi.nlm.nih.gov/pubmed/19387395http://www.nutritionandmetabolism.com/content/pdf/1743-7075-5-1.pdfhttp://www.ncbi.nlm.nih.gov/pubmed/21327797http://www.jissn.com/content/pdf/1550-2783-7-7.pdfhttp://www.ncbi.nlm.nih.gov/pubmed/11599506http://www.ncbi.nlm.nih.gov/pubmed/10978853http://www.ncbi.nlm.nih.gov/pubmed/11128859http://www.ncbi.nlm.nih.gov/pubmed/19387396http://www.ncbi.nlm.nih.gov/pubmed/12580653http://www.ncbi.nlm.nih.gov/pubmed/16004832http://www.ncbi.nlm.nih.gov/pubmed/10978853
57HMBβ-Hydroxy-β-Methylbutyrate1muscle damagerecovery–injury preventionweight training8093327010920092--Meta-analysis: Rowlands and Thomson (2009)http://www.ncbi.nlm.nih.gov/pubmed/19387395http://www.ncbi.nlm.nih.gov/pubmed/19387395http://www.ncbi.nlm.nih.gov/pubmed/11007567http://www.ncbi.nlm.nih.gov/pubmed/21327797background sources:http://www.ncbi.nlm.nih.gov/pubmed/10978853
58HMBβ-Hydroxy-β-Methylbutyrate0.5aerobic fitnessaerobic–enduranceweight training, cycling, other8093327010920092--Portal et al (2011)http://www.ncbi.nlm.nih.gov/pubmed/21327797http://www.ncbi.nlm.nih.gov/pubmed/21327797http://www.ncbi.nlm.nih.gov/pubmed/20857835http://www.ncbi.nlm.nih.gov/pubmed/21327797background sources:http://www.ncbi.nlm.nih.gov/pubmed/17469236http://www.ncbi.nlm.nih.gov/pubmed/11726262
59HMBβ-Hydroxy-β-Methylbutyrate2muscle building, fat lossfat burning–muscle buildingweight training, other8094327030920091--Meta-analysis: Rowlands and Thomson (2009)http://www.ncbi.nlm.nih.gov/pubmed/19387395http://www.ncbi.nlm.nih.gov/pubmed/19387395http://www.nutritionandmetabolism.com/content/pdf/1743-7075-5-1.pdfhttp://www.ncbi.nlm.nih.gov/pubmed/21327797http://www.jissn.com/content/pdf/1550-2783-7-7.pdfbackground sources:http://www.ncbi.nlm.nih.gov/pubmed/17469236http://www.ncbi.nlm.nih.gov/pubmed/20857835http://www.ncbi.nlm.nih.gov/pubmed/12580653http://jn.nutrition.org/content/131/7/2049.full.pdfhttp://www.ncbi.nlm.nih.gov/pubmed/11599506http://www.ncbi.nlm.nih.gov/pubmed/11128859http://www.ncbi.nlm.nih.gov/pubmed/19387396http://www.ncbi.nlm.nih.gov/pubmed/12580653
60HMB + creatine1muscle mass, strengthfat burning–muscle building, strength–powerweight trainingOTW55130A 2001 paper found creatine and HMB together can increase lean body mass and strength more than either supplement alone. They may act by different mechanisms.0000-11100.00%Jówko et al (2001)http://www.ncbi.nlm.nih.gov/pubmed/11448573http://www.ncbi.nlm.nih.gov/pubmed/11448573
61HMB + KICβ-Hydroxy-β-Methylbutyrate + alpha-Ketoisocaproate1soreness, muscle damagerecovery–injury preventionrunning, weight trainingOTW02140000-21.575.00%Nunan et al (2010)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/832/CN-00741832/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/832/CN-00741832/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/937/CN-00531937/frame.html
62Isoflavones1inflammation, oxidative stressrecovery–injury preventionrunning216034690000-3133.33%Beavers et al (2010)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/594/CN-00749594/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/594/CN-00749594/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/481/CN-00511481/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/691/CN-00424691/frame.html
63Isoflavones0muscle sorenessrecovery–injury preventionweight training216014690000-100.00%Lenn et al (2002)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/821/CN-00443821/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/821/CN-00443821/frame.html
64Isoflavones2body weight + fat loss in postmenopausal womenfat burning–muscle buildingweight training, other21602469May help overweight postmenopausal women lose weight, body fat and abdominal fat, in combination with aerobic exercise or resistance training.0000-21.575.00%Choquette et al (2011)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/410/CN-00780410/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/410/CN-00780410/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/213/CN-00609213/frame.html
65L-arginine1aerobic fitnessaerobic–endurancecycling, weight training4060416000000-4125.00%Sunderland et al (2011)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/397/CN-00785397/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/397/CN-00785397/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/910/CN-00769910/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/490/CN-00722490/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/695/CN-00702695/frame.html
66L-arginine3general exercise performancegeneral fitnessother406011600A 2011 review noted 3 out of 5 studies found significant improvements in exercise performance after short-term L-arginine supplementation and 4 out of 8 after long-term supplementation.010020110--Alvares et al (2011)http://www.ncbi.nlm.nih.gov/pubmed/21395365http://www.ncbi.nlm.nih.gov/pubmed/21395365
67L-arginine0strengthstrength–powerweight training406011600010020111--Alvares et al (2012)http://www.ncbi.nlm.nih.gov/pubmed/22251130http://www.ncbi.nlm.nih.gov/pubmed/22251130
68L-carnitine LTL-carnitine L-tartrate1metabolismfat burning–muscle buildingcycling15600313000000-30.516.67%Abramowicz and Galloway (2005)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/935/CN-00531935/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/935/CN-00531935/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/878/CN-00666878/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/630/CN-00555630/frame.html
69L-carnitine LTL-carnitine L-tartrate0enduranceaerobic–endurancecycling15600113000000-100.00%Broad et al (2005)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/630/CN-00555630/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/630/CN-00555630/frame.html
70L-carnitine LTL-carnitine L-tartrate5muscle damagerecovery–injury preventioncycling, weight training1560061300Reduces exercise-induced muscle damage and may promote muscle recovery.0000-65.591.67%Spiering et al (2008)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/968/CN-00648968/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/935/CN-00531935/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/968/CN-00648968/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/660/CN-00578660/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/081/CN-00571081/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/474/CN-00457474/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/009/CN-00377009/frame.html
71Medium chain triglycerides 0enduranceaerobic–endurancerunning8011220000-100.00%Oopik et al (2001)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/662/CN-00442662/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/662/CN-00442662/frame.html
72Phosphatidylserine1high-intensity aerobic enduranceaerobic–endurancecyclingOTW8051670000-11100.00%Kingsley et al (2006a)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/060/CN-00554060/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/060/CN-00554060/frame.html
73Phosphatidylserine0muscle damagerecovery–injury preventionrunning8051670000-100.00%Kingsley et al (2006b)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/066/CN-00572066/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/066/CN-00572066/frame.html
74Potassium phosphate1perceived exertionsports psychologyrunningOTW13901160000-11100.00%Goss et al (2001)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/833/CN-00372833/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/833/CN-00372833/frame.html
75Pyruvate0aerobic performance, metabolism, weight loss, muscle massaerobic–endurance, fat burning–muscle building, general fitnesscycling, football67723190000-200.00%Morrison et al (2000)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/300/CN-00372300/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/300/CN-00372300/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/503/CN-00742503/frame.html
76Quercetin2aerobic enduranceaerobic–endurancecycling249031990000-3266.67%Nieman et al (2010)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/310/CN-00742310/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/310/CN-00742310/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/984/CN-00734984/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/506/CN-00733506/frame.html
77Quercetin1illnesses following heavy exercisegeneral fitnesscyclingOTW24901199A trial from 2007 found quercetin reduced the number of colds experienced by cyclists after 2 weeks of intensive training.0000-11100.00%Nieman et al (2007)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/198/CN-00619198/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/198/CN-00619198/frame.html
78Quercetin0repeated sprint performanceanaerobic–high-intensityrunning249011990000-100.00%Abbey and Rankin (2011)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/586/CN-00788586/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/586/CN-00788586/frame.html
79Quercetin1inflammationrecovery–injury preventionrunning, cycling249031990000-31.550.00%Nieman et al (2009)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/037/CN-00761037/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/586/CN-00788586/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/037/CN-00761037/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/987/CN-00618987/frame.html
80Quercetin0perceived exertionsports psychologyrunning, cycling24902199A 2009 trial testing 63 ultramarathon runners competing in a 160km race found quercetin had no effect on tiredness ratings. 0000-200.00%Utter et al (2009)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/881/CN-00722881/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/881/CN-00722881/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/120/CN-00742120/frame.html
81Rhodiola Rosea L.0aerobic performanceaerobic–enduranceother8101260000-100.00%Parisi et al (2010)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/363/CN-00770363/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/363/CN-00770363/frame.html
82Rhodiola Rosea L.2muscle damagerecovery–injury preventionrowing, otherOTW8102260000-21.575.00%Skarpanska-Stejnborn et al (2009)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/769/CN-00702769/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/363/CN-00770363/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/769/CN-00702769/frame.html
83RiboseD-ribose0repeated sprint performanceanaerobic–high-intensitycycling, other149042010000-400.00%Peveler et al (2006)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/874/CN-00571874/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/629/CN-00555629/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/157/CN-00436157/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/314/CN-00435314/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/874/CN-00571874/frame.html
84RiboseD-ribose0enduranceaerobic–endurancerowing149012010000-100.00%Dunne et al (2006)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/854/CN-00561854/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/854/CN-00561854/frame.html
85RiboseD-ribose1strengthstrength–powerweight trainingOTW149022010000-2150.00%Van Gammeren et al (2002)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/658/CN-00443658/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/658/CN-00443658/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/629/CN-00374629/frame.html
86RiboseD-ribose0body compositionfat burning–muscle buildingweight training149012010000-100.00%Van Gammeren et al (2002)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/658/CN-00443658/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/658/CN-00443658/frame.html
87Sour cherry juicetart cherry juice2muscle damage + inflammationrecovery–injury preventionrunning, weight trainingOTW234230Consumed over several days, can reduce inflammation, increase antioxidant production, reduce muscle pain and speed recovery of strength after heavy exercise like weights or marathon running. 0000-22100.00%Howatson et al (2010)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/068/CN-00778068/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/068/CN-00778068/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/005/CN-00566005/frame.html
88Soy protein1high intensity enduranceaerobic–endurance, anaerobic–high-intensitycyclingOTW241001424In a 2010 trial, soy protein + carbohydrate increased time-to-exhaustion in male cyclists by 37% relative to carbohydrate alone. 0000-11100.00%Ghosh et al (2010)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/777/CN-00759777/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/777/CN-00759777/frame.html
89Soy protein1calorie + fat burning in postmenopausal womenfat burning–muscle buildingweight trainingOTW241002424Might enhance the calorie-burning effects of exercise. A 2010 study of 60 postmenopausal women found those in the soy + weight training group burned 48 calories per day more than the placebo + weights group.0000-2150.00%Trevisan et al (2010)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/204/CN-00802204/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/204/CN-00802204/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/125/CN-00586125/frame.html
90SpirulinaSpirulina platensis2endurance performanceaerobic–endurancerunningOTW76702483-4 weeks of spirulina delayed fatigue among trained and untrained trial runners, possibly by sparing carb fuel and increasing fat metabolism, or preventing muscle damage. 0000-22100.00%Kalafati et al (2010)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/748/CN-00732748/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/748/CN-00732748/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/943/CN-00571943/frame.html
91SpirulinaSpirulina platensis2muscle damage, fat burningrecovery–injury prevention, fat burning–muscle buildingrunningOTW76702480000-22100.00%Lu et al (2006)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/943/CN-00571943/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/748/CN-00732748/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/943/CN-00571943/frame.html
92Taurine0.5endurance performance, metabolismaerobic–endurance, fat burning–muscle buildingcyclingOTW256015751.66 grams of taurine - a can of energy drink contains 1 gram - before a time trial did not enhance trained cyclists' performance but did slightly increase fat burning.0000-10.550.00%Rutherford et al (2010)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/746/CN-00762746/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/746/CN-00762746/frame.html
93Tribulus terrestrisdevil's thorn, tackweed0strength, body composition, testosteronestrength–power, fat burning-muscle buildingweight training2190339Previously thought to affect testosterone, posing a possible doping test risk, but a 2007 study found T. Terrestris had no effects on this hormone.0000-300.00%Rogerson et al (2007)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/231/CN-00589231/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/231/CN-00589231/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/025/CN-00332025/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/836/CN-00297836/frame.html
94Tyrosine1exercise tolerance in hot conditionsaerobic–endurance, sports psychologycyclingOTW23401164By boosting dopamine - a feel-good chemical - it may enable better heat tolerance. Cyclists given tyrosine in a 2011 study cycled significantly longer than those given a placebo. 0000-11100.00%Tumilty et al (2011)http://www.ncbi.nlm.nih.gov/pubmed/21437603http://www.ncbi.nlm.nih.gov/pubmed/21437603
95Velvet antlerDeer velvet antler, elk velvet antler0endurance, strength, hormonal exercise responseaerobic–endurance, strength–power, general fitnessrowing, weight training134024Made from the antlers of deer or elk. In a 2003 trial, it provided some strength and endurance gains against placebo, but more research is needed.0000-20.525.00%Syrotuik et al (2005)http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/934/CN-00531934/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/934/CN-00531934/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/523/CN-00459523/frame.html
96Whey protein3weight + fat lossfat burning–muscle buildingweight training86103320Helps you shed fat without losing muscle too. In a 2011 study, those taking whey protein lost more weight and fat than those consuming the same daily calories as carbs. 0000-33100.00%Baer et al (2009)http://www.ncbi.nlm.nih.gov/pubmed/21677076http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/061/CN-00575061/frame.htmlhttp://www.ncbi.nlm.nih.gov/pubmed/21677076http://www.ncbi.nlm.nih.gov/pubmed/18371214
97Whey protein6strength, muscle building + recoverystrength–power, recovery–injury prevention weight training, running861011320A majority of trials show whey protein - derived from milk - improves strength, helps build muscles and speeds recovery. May have the edge over other proteins: a 2009 study found muscle protein synthesis after whey consumption was 122% greater than casein and 31% greater than soy. 0000-111090.91%Tang et al (2009)http://www.ncbi.nlm.nih.gov/pubmed/19589961http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/142/CN-00772142/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/448/CN-00743448/frame.htmlhttp://www.ncbi.nlm.nih.gov/pubmed/19589961http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/003/CN-00722003/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/095/CN-00733095/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/200/CN-00578200/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/671/CN-00628671/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/535/CN-00571535/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/061/CN-00575061/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/262/CN-00490262/frame.htmlhttp://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/987/CN-00516987/frame.html