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k-dense-ai--scientific-agen…/skills/bids/references/bids_specification.md
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BIDS Specification Reference

Note

: The canonical, machine-readable source of truth is bids_schema.json (in this directory), exported from the BIDS Schema. The tables below are a human-readable summary. When the two disagree, trust the schema.

Entity Table

Complete list of BIDS entities, their keys, and where they apply. Rows are listed in the required filename ordering — entities must appear in this order in BIDS filenames. This order is defined in the schema at rules.entities (see bids_schema.json).

# Entity Key Format Applies to
1 Subject sub- <label> (alphanumeric) All files (required)
2 Template tpl- <label> derivatives (template-based)
3 Session ses- <label> All datatypes
4 Cohort cohort- <label> derivatives (template cohorts)
5 Sample sample- <label> microscopy
6 Task task- <label> func, eeg, meg, ieeg, beh, pet, nirs, motion
7 Tracking system tracksys- <label> motion
8 Acquisition acq- <label> All datatypes
9 Nucleus nuc- <label> MR spectroscopy
10 Volume voi- <label> MR spectroscopy
11 Contrast enhancing agent ce- <label> anat
12 Tracer trc- <label> pet
13 Stain stain- <label> microscopy
14 Reconstruction rec- <label> anat, func, pet
15 Direction dir- <label> fmap, dwi, perf, func
16 Run run- <index> (integer) All datatypes
17 Modality mod- <label> fieldmaps
18 Echo echo- <index> func, fmap
19 Flip flip- <index> anat (quantitative MRI)
20 Inversion inv- <index> anat (quantitative MRI)
21 Magnetization transfer mt- on/off anat (quantitative MRI)
22 Part part- mag/phase/real/imag anat, func
23 Processing proc- <label> eeg, meg, ieeg
24 Hemisphere hemi- L/R derivatives (surface data)
25 Space space- <label> derivatives
26 Split split- <index> func, dwi, eeg, meg, ieeg
27 Recording recording- <label> physio, stim, eeg, meg
28 Chunk chunk- <index> large files split across chunks
29 Atlas atlas- <label> derivatives (atlas-based)
30 Segmentation seg- <label> derivatives
31 Scale scale- <label> derivatives
32 Resolution res- <label> derivatives
33 Density den- <label> derivatives (surface meshes)
34 Label label- <label> derivatives (segmentation labels)
35 Description desc- <label> derivatives only

Datatypes (Top-Level Directories)

Datatype Description Common Suffixes
anat Structural MRI T1w, T2w, FLAIR, T2star, inplaneT1, inplaneT2, PDw, T1map, T2map, T1rho, UNIT1, MP2RAGE, MTR, MTS
func Functional MRI bold, cbv, sbref
dwi Diffusion-weighted imaging dwi, sbref
fmap Fieldmaps phasediff, phase1, phase2, magnitude1, magnitude2, fieldmap, epi
perf Perfusion imaging (ASL) asl, m0scan, aslcontext
eeg Electroencephalography eeg, channels, electrodes, events, coordsystem
meg Magnetoencephalography meg, channels, coordsystem, events, headshape
ieeg Intracranial EEG ieeg, channels, electrodes, events, coordsystem
pet Positron Emission Tomography pet, blood
micr Microscopy 2PE, BF, CARS, CONF, DIC, DF, FLUO, MPE, NLO, OCT, PC, PLI, SRS, TL
beh Behavioral data (no imaging) events, beh, physio, stim
motion Motion capture motion, channels, events
nirs Near-infrared spectroscopy nirs, channels, optodes, coordsystem, events

File Extensions

Extension Description
.nii.gz Compressed NIfTI (standard for MRI/fMRI/DWI)
.nii Uncompressed NIfTI
.json JSON sidecar metadata
.tsv Tab-separated values (events, participants, etc.)
.bvec b-vectors (DWI gradient directions)
.bval b-values (DWI gradient strengths)
.edf European Data Format (EEG)
.bdf BioSemi Data Format (EEG)
.vhdr/.vmrk/.eeg BrainVision format (EEG)
.set EEGLAB format (EEG)
.fif Elekta/MEGIN format (MEG)
.ds CTF dataset (MEG)
.sqd/.con KIT/Yokogawa (MEG)

Required Files

Dataset-level (always required)

  • dataset_description.json
  • README or README.md
  • CHANGES
  • participants.tsv + participants.json
  • LICENSE
  • sub-<label>/[ses-<label>/]sub-<label>[_ses-<label>]_scans.tsv - per-run acquisition metadata

Modality-specific required files

  • func/bold: corresponding _events.tsv for task data; TaskName in JSON sidecar
  • dwi: .bvec and .bval files
  • eeg/meg/ieeg: _channels.tsv, _events.tsv
  • perf/asl: _aslcontext.tsv

Directory Structure Rules

  1. Subject directories are named sub-<label> and sit at dataset root
  2. Session directories ses-<label> are optional; if used, must be used for ALL subjects
  3. Datatype directories (anat/, func/, etc.) sit inside subject (or session) directories
  4. sourcedata/ stores raw unprocessed data (DICOM, etc.) - not validated
  5. derivatives/ stores processed outputs - each pipeline in its own subdirectory
  6. code/ stores analysis scripts
  7. stimuli/ stores stimulus files used during acquisition
  8. phenotype/ stores questionnaire/behavioral data not tied to specific imaging

Metadata Inheritance

JSON metadata cascades from higher to lower directories. If the same key appears at multiple levels, the most specific (closest to the data file) wins.

Resolution order (highest priority first):

  1. File-level sidecar: sub-01/func/sub-01_task-rest_bold.json
  2. Subject-level sidecar: sub-01/sub-01_task-rest_bold.json
  3. Dataset-level sidecar: task-rest_bold.json

This avoids duplicating metadata that is constant across subjects (e.g., RepetitionTime, TaskName).

Standard Template Spaces

Common space- values used in derivatives:

Space Label Description
MNI152NLin2009cAsym MNI 2009c nonlinear asymmetric (fMRIPrep default)
MNI152NLin6Asym MNI 6th-generation nonlinear asymmetric (FSL default)
MNI152Lin MNI linear registration
MNIPediatricAsym Pediatric MNI templates
T1w Individual subject's T1w native space
fsnative FreeSurfer individual surface space
fsaverage FreeSurfer average surface (164k vertices)
fsaverage5 FreeSurfer average surface (10k vertices)
fsaverage6 FreeSurfer average surface (40k vertices)
fsLR HCP fs_LR surface space
OASIS30ANTs OASIS-30 ANTs template
UNCInfant UNC infant templates

Full list managed by TemplateFlow: https://www.templateflow.org/

Specification Changelog (Selected)

Version Key Changes
1.10.0 Motion capture modality; refined derivative entity rules
1.9.0 NIRS modality; Python-based validator reference implementation
1.8.0 Microscopy modality; chunk- entity for large files
1.7.0 PET modality fully specified
1.6.0 EEG/MEG/iEEG matured; _coordsystem.json
1.5.0 Genetic descriptors; ASL perfusion
1.4.0 dataset_description.json expanded; derivatives framework
1.0.0 Initial release: MRI only (anat, func, dwi, fmap)

Entity Label Rules

  • Labels (<label>): alphanumeric only, no special characters, no leading zeros (except run-)
  • Indices (<index>): non-negative integers, zero-padded to equal width within a dataset (e.g., run-01, run-02)
  • Subject labels: typically numeric (01, 02) but can be alphanumeric (CON01, PAT01)
  • Session labels: descriptive (pre, post, baseline, followup) or numeric
  • Task labels: brief, descriptive, no spaces (rest, nback, faces, gonogo)